MTP 082Obesity: What Works, How, Why, and When?Clinical questions to be addressed:How effective is lifestyle modification in reducing weight and other clinical/comorbid end points?Which drugs are most effective and safe? How long can drugs be continued safely?Which patients are eligible for bariatric surgery, and is one technique preferred over another for primary surgery?Is bariatric surgery more effective and durable than medical management for obesity?What are the major medical issues that arise after bariatric surgery?