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Diabetes for the Internist
PRE 903 Tuesday, 8:00 a.m.-5:00 p.m.
Harold E. Lebovitz, MD
Professor of Medicine, Department of Medicine, State University of New York Health Science Center at Brooklyn, Brooklyn, NY

The issues involved in the management of diabetes mellitus and its complications have become more clinically relevant as the epidemics of diabetes and obesity continue to intensify. This Pre-Course will provide the internist with the latest information about the abnormalities that underlie the development and progression of both type 1 and type 2diabetes and how these abnormalities influence therapeutic decisions. It will emphasize the rationale and current controversies for the practical application of newer treatment strategies and pharmacologic agents for hyperglycemia. It will discuss the role of newer treatments compared with older and less expensive generic treatments. Newer studies concerning the management of hypertension, hyperlipidemia, and other cardiovascular risk factors (multifactorial management) in the context of hyperglycemia will be emphasized. The complex issue of prevention of diabetes, as well as the role of pharmacologic agents in decreasing ß-cell apoptosis or even increasing ß-cell mass, will be debated. The new field of matching genetic type with specific therapies will be presented. The emphasis throughout the course, where possible, will be on strategies to improve clinical outcomes rather than surrogate end points.

Learning Objectives:

1. Design glycemic treatment strategies based on an analysis of the risk--benefit ratio of available pharmacologic agents.
2. Effectively use available incretin mimetic and incretin-sparing therapies.
3. Develop insulin treatment programs that are appropriate for each individual patient.
4. Use glucose-monitoring devices in a cost-effective manner.
5. Reduce clinical cardiovascular events by appropriately treating cardiovascular risk factors.