Clinical questions to be addressed: 1. How is chronic kidney disease defined? What therapeutic modalities can slow the progression of chronic kidney disease? 2. When should patients with chronic kidney disease be referred? 3. What is the role of ACE inhibitors and ARBs in the treatment of patients with chronic kidney disease? 4. What diets are recommended for patients with chronic kidney disease? 5. What is the relationship of chronic kidney disease to cardiovascular disease? 6. What are the long-term graft and patient survival rates for living donor and deceased donor transplants?