1. What is the role of glycemic control in diabetic patients with acute infections? 2. What are important treatment or monitoring issues in managing the immunocompromised patient with a severe infection (role of GCSF, modify immunosupressives, IV vs. oral therapy, double coverage)? 3. Management of severe necrotizing skin infections: role of surgical management. Are any antibiotics preferable? 4. Management of severe limb infection in the diabetic patient