Clinical questions to be addressed:Additional insights regarding hormone replacement therapy: the Women's Health Initiative and related studies.Lipid-lowering with statins: type 2 Diabetes; intensive treatment targets; safety; and implications for practice.Cancer screening: prostate and breastLow carbohydrate diets - do they work and are they safe?Hypertension: role of home BP monitoring.Recurrent DVT and D-DimerPrevention: Exercise, Vitamin D, others