Clinical questions to be addressed:Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia.Effects of systematic prone positioning in hypoxemic acute respiratory failure: a randomized controlled trial.Effect of recombinant surfactant protein C-based surfactant on the acute respiratory distress syndrome.Use of B-type natriuretic peptide in the evaluation and management of acute dyspnea.Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial.Measurement of serum free cortisol in critically ill patients.A comparison of albumin and saline for fluid resuscitation in the intensive care unitNoninvasive positive-pressure ventilation for respiratory failure after extubation.The National Heart, Lung, and Blood Institute ARDS Clinical trials Network. Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome