Clinical questions to be addressed:How should systolic hypertension be treated in elderly patients?When should renal artery disease be suspected in a patient? What therapies are effective for patients with clinically significant renal artery disease? Does renal insufficiency signficantly affect diagnosis and treatment?How does the physician use renin/aldosterone ratios to refine diagnostic accuracy?Is pheochromocytoma an important consideration in the differential diagnosis of secondary hypertension?What is the practical approach to office-based therapy of hypertensive urgencies and emergencies?