Clinical questions to be addressed:REPRODUCTIVE HORMONESIs Symptom Relief with HRT during menopause worth the risks?Would growth hormone be an effective anabolic adjunct in HIV-infected men?Is Sildenafil safe in men with congestive heart failure?THYROID HORMONESDo excesses of thyroid hormone increase miscarriage rates?What are the risks to thyroid function in patients with Hepatitis C undergoing combination treatment with interferon alfa and ribavirin?Does addition of triiodothyronine (T3) to levothyroxine (T4) therapy for hypothyroidism improve well-being and clinical responses?Should æsubclinical hypothyroidismÆ be treated with levothyroxine?ADRENAL HORMONESDo corticosteroids improve outcomes in patients with septic shock?Should we be distinguishing between true adrenal insufficiency in the ICU and reduced plasma cortisol secondary to protein binding changes?Is there a linear relationship between serum aldosterone levels and risk of hypertension?DIABETES MELLITUSWhen should angiotensin receptor antagonists be started in hypertensive diabetics?Is stress testing sufficient to detect myocardial ischemia in diabetics?Should Diabetic Ketoacidosis (DKA) be managed in the ICU?Can glycosylated hemoglobin levels serve as a predictor for cardiovascular disease (CVD) events ?What are the newest and most novel approaches to diabetes management for the future?LIPIDSHow effective are lipid lowering agents in diabetics?How much should LDL be lowered to benefit coronary risk?Does statin therapy promise benefit for stroke reduction as well as coronary disease reduction?How much more efficacious is statin plus ezetimibe therapy than administration of a statin alone?What endocrine problem other than hyperthyroidism is associated with atrial fibrillation ?