MTP 052 Clinical questions to be addressed: When should acute HIV infection be suspected? What should the internist know about highly active antiretroviral therapy (HAART)? What are the indications for initiating HAART? Discontinuing and changing HAART? Are there any indications for urgent initiation of HAART? What are common and significant side effects and complications associated with HAART (diabetes, hyperlipidemia, etc.)? What are the most common opportunistic infections in the era of HAART therapy?