MTP 046 Clinical questions to be addressed: What are the malignant and non-malignant causes of the hypercoagulable state? What are the best therapeutic options for patients with the hypercoagulable state due to cancer? What are the roles of the different heparin preparations, fondaparinux, warfarin and IVC filters? What are the indications for testing for the factor V Leiden and prothrombin gene mutations and feciciencies of anthrombin, protein C and protein S?